Retrieve a specific pathway in the GPML format

getPathway(pathway, revision = 0)

Arguments

pathway

WikiPathways identifier (WPID) for the pathway to download, e.g. WP4

revision

(integer, optional) Number to indicate a specific revision to download

Value

GPML

Examples

{ getPathway('WP554') }
#> [[1]] #> [1] "<?xml version=\"1.0\" encoding=\"UTF-8\"?>\n<Pathway xmlns=\"http://pathvisio.org/GPML/2013a\" Name=\"ACE Inhibitor Pathway\" Organism=\"Homo sapiens\">\n <Comment Source=\"WikiPathways-description\">The core of this pathway was elucidated over a century ago and involves the conversion of angiotensinogen to angiotensin I (Ang I) by renin, its subsequent conversion to angiotensin II (Ang II) by angiotensin converting enzyme. Ang II activates the angiotensin II receptor type 1 to induce aldosterone synthesis, increasing water and salt resorption and potassium excretion in the kidney and increasing blood pressure.\n\nSource: PharmGKB (https://www.pharmgkb.org/pathway/PA2023)\n\nProteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP554 CPTAC Assay Portal]</Comment>\n <BiopaxRef>b93</BiopaxRef>\n <Graphics BoardWidth=\"991.0\" BoardHeight=\"651.0\" />\n <DataNode TextLabel=\"NOS3\" GraphId=\"ab119\" Type=\"GeneProduct\">\n <Attribute Key=\"org.pathvisio.model.BackpageHead\" Value=\"NOS3 | nitric oxide synthase 3 (endothelial cel...\" />\n <Graphics CenterX=\"759.0\" CenterY=\"512.3333333333333\" Width=\"60.0\" Height=\"20.0\" ZOrder=\"32768\" FontSize=\"10\" Valign=\"Middle\" />\n <Xref Database=\"Entrez Gene\" ID=\"4846\" />\n </DataNode>\n <DataNode TextLabel=\"AGTR2\" GraphId=\"b1122\" Type=\"GeneProduct\">\n <BiopaxRef>bc9</BiopaxRef>\n <Attribute Key=\"org.pathvisio.model.BackpageHead\" Value=\"AGTR2 | angiotensin II receptor type 2\" />\n <Graphics CenterX=\"351.3333333333333\" CenterY=\"390.3333333333333\" Width=\"60.0\" Height=\"20.0\" ZOrder=\"32768\" FontSize=\"10\" Valign=\"Middle\" />\n <Xref Database=\"Entrez Gene\" ID=\"186\" />\n </DataNode>\n <DataNode TextLabel=\"Ang 1-5\" GraphId=\"b298c\" Type=\"Metabolite\">\n <Graphics CenterX=\"102.0\" CenterY=\"326.0\" Width=\"54.0\" Height=\"20.0\" ZOrder=\"32768\" FontSize=\"10\" Valign=\"Middle\" Color=\"0000ff\" />\n <Xref Database=\"KEGG Compound\" ID=\"C15852\" />\n </DataNode>\n <DataNode TextLabel=\"BDKRB1\" GraphId=\"b4349\" Type=\"GeneProduct\">\n <Graphics CenterX=\"681.5\" CenterY=\"388.0\" Width=\"57.0\" Height=\"20.0\" ZOrder=\"32768\" FontSize=\"10\" Valign=\"Middle\" />\n <Xref Database=\"Entrez Gene\" ID=\"623\" />\n </DataNode>\n <DataNode TextLabel=\"TFs\" GraphId=\"b47da\" Type=\"GeneProduct\">\n <Graphics CenterX=\"395.5\" CenterY=\"469.0\" Width=\"37.0\" Height=\"20.0\" ZOrder=\"32768\" FontSize=\"10\" Valign=\"Middle\" />\n <Xref Database=\"\" ID=\"\" />\n </DataNode>\n <DataNode TextLabel=\"AGTR1\" GraphId=\"b4811\" Type=\"GeneProduct\">\n <Attribute Key=\"org.pathvisio.model.BackpageHead\" Value=\"AGTR1 | angiotensin II receptor type 1\" />\n <Graphics CenterX=\"428.3333333333333\" CenterY=\"390.3333333333333\" Width=\"60.0\" Height=\"20.0\" ZOrder=\"32768\" FontSize=\"10\" Valign=\"Middle\" />\n <Xref Database=\"Entrez Gene\" ID=\"185\" />\n </DataNode>\n <DataNode TextLabel=\"Aldosterone\" GraphId=\"b75c3\" Type=\"Metabolite\">\n <BiopaxRef>ce3</BiopaxRef>\n <Graphics CenterX=\"563.0\" CenterY=\"530.0\" Width=\"80.0\" Height=\"20.0\" ZOrder=\"32768\" FontSize=\"10\" Valign=\"Middle\" Color=\"0000ff\" />\n <Xref Database=\"HMDB\" ID=\"HMDB0000037\" />\n </DataNode>\n <DataNode TextLabel=\"TGFB1\" GraphId=\"becdd\" Type=\"GeneProduct\">\n <BiopaxRef>af8</BiopaxRef>\n <Graphics CenterX=\"192.5\" CenterY=\"481.0\" Width=\"59.0\" Height=\"20.0\" ZOrder=\"32768\" FontSize=\"10\" Valign=\"Middle\" />\n <Xref Database=\"Entrez Gene\" ID=\"7040\" />\n </DataNode>\n <DataNode TextLabel=\"Bradykinin\" GraphId=\"c496e\" Type=\"Metabolite\">\n <Graphics CenterX=\"717.0\" CenterY=\"319.0\" Width=\"80.0\" Height=\"20.0\" ZOrder=\"32768\" FontSize=\"10\" Valign=\"Middle\" Color=\"0000ff\" />\n <Xref Database=\"HMDB\" ID=\"HMDB0004246\" />\n </DataNode>\n <DataNode TextLabel=\"CTSG\" GraphId=\"c9ca8\" Type=\"GeneProduct\">\n <Graphics CenterX=\"321.5\" CenterY=\"231.0\" Width=\"60.0\" Height=\"20.0\" ZOrder=\"32768\" FontSize=\"10\" Valign=\"Middle\" />\n <Xref Database=\"Entrez Gene\" ID=\"1511\" />\n </DataNode>\n <DataNode TextLabel=\"Angiotensin II\" GraphId=\"ca3ad\" Type=\"Metabolite\">\n <Graphics CenterX=\"383.0\" CenterY=\"326.0\" Width=\"80.0\" Height=\"20.0\" ZOrder=\"32768\" FontSize=\"10\" Valign=\"Middle\" Color=\"0000ff\" />\n <Xref Database=\"HMDB\" ID=\"HMDB0001035\" />\n </DataNode>\n <DataNode TextLabel=\"KNG1\" GraphId=\"cc0b4\" Type=\"GeneProduct\">\n <Attribute Key=\"org.pathvisio.model.BackpageHead\" Value=\"KNG1 | kininogen 1\" />\n <Graphics CenterX=\"717.6666666666667\" CenterY=\"247.33333333333331\" Width=\"60.0\" Height=\"20.0\" ZOrder=\"32768\" FontSize=\"10\" Valign=\"Middle\" />\n <Xref Database=\"Entrez Gene\" ID=\"3827\" />\n </DataNode>\n <DataNode TextLabel=\"Ca++\" GraphId=\"d519e\" Type=\"Metabolite\">\n <Graphics CenterX=\"371.0\" CenterY=\"425.0\" Width=\"32.0\" Height=\"20.0\" ZOrder=\"32768\" FontSize=\"10\" Valign=\"Middle\" Color=\"0000ff\" />\n <Xref Database=\"HMDB\" ID=\"HMDB0000464\" />\n </DataNode>\n <DataNode TextLabel=\"Angiotensin I\" GraphId=\"d6a08\" Type=\"Metabolite\">\n <Graphics CenterX=\"382.0\" CenterY=\"201.0\" Width=\"80.0\" Height=\"20.0\" ZOrder=\"32768\" FontSize=\"10\" Valign=\"Middle\" Color=\"0000ff\" />\n <Xref Database=\"PubChem-compound\" ID=\"3081372\" />\n </DataNode>\n <DataNode TextLabel=\"ACE\" GraphId=\"d6f1e\" Type=\"GeneProduct\">\n <Attribute Key=\"org.pathvisio.model.BackpageHead\" Value=\"ACE | angiotensin I converting enzyme (peptidyl...\" />\n <Graphics CenterX=\"652.3333333333333\" CenterY=\"283.66666666666663\" Width=\"60.0\" Height=\"20.0\" ZOrder=\"32768\" FontSize=\"10\" Valign=\"Middle\" />\n <Xref Database=\"Entrez Gene\" ID=\"1636\" />\n </DataNode>\n <DataNode TextLabel=\"ACE Inhibitor\" GraphId=\"d9620\" Type=\"Metabolite\">\n <Attribute Key=\"org.pathvisio.model.BackpageHead\" Value=\"ACE Inhibitor\" />\n <Graphics CenterX=\"467.5\" CenterY=\"40.66666666666666\" Width=\"91.0\" Height=\"20.0\" ZOrder=\"32768\" FontSize=\"10\" Valign=\"Middle\" Color=\"cc0000\" />\n <Xref Database=\"ChEBI\" ID=\"CHEBI:35457\" />\n </DataNode>\n <DataNode TextLabel=\"Deoxycorticosterone\" GraphId=\"da9ee\" Type=\"Metabolite\">\n <Graphics CenterX=\"407.875\" CenterY=\"529.75\" Width=\"113.75\" Height=\"20.0\" ZOrder=\"32768\" FontSize=\"10\" Valign=\"Middle\" Color=\"0000ff\" />\n <Xref Database=\"HMDB\" ID=\"HMDB0000016\" />\n </DataNode>\n <DataNode TextLabel=\"CMA1\" GraphId=\"de1e4\" Type=\"GeneProduct\">\n <Graphics CenterX=\"301.0\" CenterY=\"257.0\" Width=\"60.0\" Height=\"20.0\" ZOrder=\"32768\" FontSize=\"10\" Valign=\"Middle\" />\n <Xref Database=\"Entrez Gene\" ID=\"1215\" />\n </DataNode>\n <DataNode TextLabel=\"Ang 1-7\" GraphId=\"df262\" Type=\"Metabolite\">\n <Graphics CenterX=\"204.5\" CenterY=\"326.0\" Width=\"51.0\" Height=\"20.0\" ZOrder=\"32768\" FontSize=\"10\" Valign=\"Middle\" Color=\"0000ff\" />\n <Xref Database=\"Chemspider\" ID=\"110354\" />\n </DataNode>\n <DataNode TextLabel=\"Prostacyclin\" GraphId=\"e01c3\" Type=\"Metabolite\">\n <Graphics CenterX=\"693.0\" CenterY=\"466.0\" Width=\"70.0\" Height=\"20.0\" ZOrder=\"32768\" FontSize=\"10\" Valign=\"Middle\" Color=\"0000ff\" />\n <Xref Database=\"PubChem-compound\" ID=\"114805\" />\n </DataNode>\n <DataNode TextLabel=\"REN\" GraphId=\"e0a11\" Type=\"GeneProduct\">\n <Attribute Key=\"org.pathvisio.model.BackpageHead\" Value=\"REN | renin\" />\n <Graphics CenterX=\"319.08123249299706\" CenterY=\"118.94957983193277\" Width=\"44.66666666666663\" Height=\"20.0\" ZOrder=\"32768\" FontSize=\"10\" Valign=\"Middle\" />\n <Xref Database=\"Entrez Gene\" ID=\"5972\" />\n </DataNode>\n <DataNode TextLabel=\"CYP11B2\" GraphId=\"e14ac\" Type=\"GeneProduct\">\n <BiopaxRef>ce3</BiopaxRef>\n <Graphics CenterX=\"491.0\" CenterY=\"479.0\" Width=\"62.0\" Height=\"20.0\" ZOrder=\"32768\" FontSize=\"10\" Valign=\"Middle\" />\n <Xref Database=\"Entrez Gene\" ID=\"1585\" />\n </DataNode>\n <DataNode TextLabel=\"MAS1\" GraphId=\"e3012\" Type=\"GeneProduct\">\n <BiopaxRef>c74</BiopaxRef>\n <Graphics CenterX=\"204.0\" CenterY=\"389.0\" Width=\"52.0\" Height=\"20.0\" ZOrder=\"32768\" FontSize=\"10\" Valign=\"Middle\" />\n <Xref Database=\"Entrez Gene\" ID=\"4142\" />\n </DataNode>\n <DataNode TextLabel=\"ACE2\" GraphId=\"e68e0\" Type=\"GeneProduct\">\n <BiopaxRef>c74</BiopaxRef>\n 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rdf:datatype=\"http://www.w3.org/2001/XMLSchema#string\">18729003</bp:ID>\n <bp:DB rdf:datatype=\"http://www.w3.org/2001/XMLSchema#string\">PubMed</bp:DB>\n <bp:TITLE rdf:datatype=\"http://www.w3.org/2001/XMLSchema#string\">Mineralocorticoid receptor antagonists and endothelial function.</bp:TITLE>\n <bp:SOURCE rdf:datatype=\"http://www.w3.org/2001/XMLSchema#string\">Curr Opin Investig Drugs</bp:SOURCE>\n <bp:YEAR rdf:datatype=\"http://www.w3.org/2001/XMLSchema#string\">2008</bp:YEAR>\n <bp:AUTHORS rdf:datatype=\"http://www.w3.org/2001/XMLSchema#string\">Maron BA</bp:AUTHORS>\n <bp:AUTHORS rdf:datatype=\"http://www.w3.org/2001/XMLSchema#string\">Leopold JA</bp:AUTHORS>\n </bp:PublicationXref>\n <bp:openControlledVocabulary xmlns:bp=\"http://www.biopax.org/release/biopax-level3.owl#\">\n <bp:TERM xmlns:rdf=\"http://www.w3.org/1999/02/22-rdf-syntax-ns#\" rdf:datatype=\"http://www.w3.org/2001/XMLSchema#string\">angiotensin signaling pathway</bp:TERM>\n <bp:ID xmlns:rdf=\"http://www.w3.org/1999/02/22-rdf-syntax-ns#\" rdf:datatype=\"http://www.w3.org/2001/XMLSchema#string\">PW:0000245</bp:ID>\n <bp:Ontology xmlns:rdf=\"http://www.w3.org/1999/02/22-rdf-syntax-ns#\" rdf:datatype=\"http://www.w3.org/2001/XMLSchema#string\">Pathway Ontology</bp:Ontology>\n </bp:openControlledVocabulary>\n </Biopax>\n</Pathway>" #>